Pharm., 1882, p. 521). U.S. Environmental Protection Agency (EPA), "A Brief History of Thyme - Hungry History", "Sur la composition de l'huile essentielle de thym", "Ueber eine Synthese von Thymol aus Cuminol", "Biological Activities of Three Essential Oils of the Lamiaceae Family", "Thymol and carvacrol: biotransformation and antifungal activity against the plant pathogenic fungi Colletotrichum acutatum and Botryodiplodia theobromae", "Composition and Antimicrobial Activity of, "The Essential Oil of Monarda didyma L. (Lamiaceae) Exerts Phytotoxic Activity In Vitro against Various Weed Seeds", https://en.wikipedia.org/w/index.php?title=Thymol&oldid=986742896, GABAA receptor positive allosteric modulators, Articles with incomplete citations from August 2017, Short description is different from Wikidata, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles with unsourced statements from December 2019, Creative Commons Attribution-ShareAlike License, 49 to 51 °C (120 to 124 °F; 322 to 324 K), Iridoid glycosides (iridoids bound to a sugar), Terpene synthase enzymes (many), having in common a, This page was last edited on 2 November 2020, at 19:08.

A tisane made from them was also used to treat mouth and throat infections caused by dental caries and gingivitis. This latter is held in the patient's mouth, who will aspire the air charged with the vapor of the thymol.

[14] In 1853, the French chemist Alexandre Lallemand named thymol and determined its empirical formula.

An increase in the quantity of urine was frequently noticed; and the urine presented a dark, greenish color, as if it contained blood, and appeared a yellowish-brown when illuminated by reflected light. Its alcoholic solution is optically inactive"—(U. S. P.).
Then top off back the the original fill level with alcohol. Thyme was also used as incense and placed on coffins during funerals, as it was supposed to assure passage into the next life. Jour. [7] Thymol is produced from m-cresol and propene in the gas phase:[8], Ancient Egyptians used thyme for embalming.

Concentrated thymol may be advantageously substituted for nitric acid, or nitrate of silver, in cauterization of the dental nerves; its odor is not so disagreeable as that of carbolic acid.

Related Preparation.—LISTERINE.

M. Lewin considers thymol very useful in diphtheria and other similar diseases dependent upon the action of living organisms; also in arresting the hypersecretion of various mucous membranes. Thymol has been employed in inhalations, by Bouillhon, Paquet, and others, in bronchial and other affections of the respiratory organs, attended with gangrenous exhalations.

Each of CleanWell's thymol cleaning products contains a 0.05% concentration of thymol and is designed to kill 99.9% of germs, bacteria, and viruses. [6], Regions lacking natural sources of thymol obtain the compound via total synthesis. These solutions may be applied on lint, or by spray. The spread of thyme throughout Europe was thought to be due to the Romans, as they used it to purify their rooms and to "give an aromatic flavour to cheese and liqueurs". Mix. Nychas G.J.E. It should be kept in well-stoppered bottles"—(U. S. P.).

[23] People of the Middle East continue to use za'atar, a delicacy made with large amounts of thyme, to reduce and eliminate internal parasites. Ecotoxicol.Environ Saf 2009;72(3):943-947. S. P.). Mix. When much hyperemia is present, it must not be applied until this has been allayed. A cathartic is administered at night, and 10 grains of thymol administered in the morning every 15 minutes until the worm is expelled. The antibacterial properties of thymol, a major part of thyme essential oil, as well as other constituents, are in part associated with their lipophilic character, leading to accumulation in bacterial membranes and subsequent membrane-associated events, such as energy depletion. In doses of from 30 to 60 grains, M. Baelz considers its action, as an antipyretic, decidedly inferior to that of salicylic acid. [15] Thymol was first synthesized by the Swedish chemist Oskar Widman in 1882.

Thymol has been used to successfully control varroa mites and prevent fermentation and the growth of mold in bee colonies, methods developed by beekeeper R. O. It suppresses the gangrenous odor, and prevents the diseased bronchial surfaces and the abnormal secretions covering them, from undergoing butyric fermentation, thus checking a poisoning of the blood.


The effects of thymol on sister chromatid exchange, chromosome aberration and micronucleus in human lymphocytes. Thymol also provides the distinctive, strong flavor of the culinary herb thyme, also produced from T. vulgaris.

Thymol is a component found in thyme oil, which is a naturally occurring mixture of compounds from, yup, the thyme plant, according to the EPA.

They're also alcohol … [17] In vitro studies have found thymol to be useful as an antifungal against food spoilage and bovine mastitis. It may be used freely, full strength or diluted, as a gargle, mouth-wash, spray, injection or inhalation. The Blackfoot Native Americans recognized these plants' strong antiseptic action, and used poultices of the plants for skin infections and minor wounds. This substance is analogous to phenacetin, inasmuch as the phenol of the latter is substituted by thymol. [22], Thymol has been used in alcohol solutions and in dusting powders for the treatment of tinea or ringworm infections, and was used in the United States to treat hookworm infections. of a 10 per cent solution of sodium hydrate, a clear, colorless, or very slightly reddish solution should be formed, which becomes darker on standing, but without the separation of oily drops (absence of thymen, or laevogyrate pinene (C10H16).

[citation needed] It is also used as a preservative in halothane, an anaesthetic, and as an antiseptic in mouthwash. Thymol is only slightly soluble in water at neutral pH, but it is extremely soluble in alcohols and other organic solvents. Fifteen grains of thymol dissolved in 2 pints of distilled water, forms an invaluable disinfectant; this has been found effective in disinfecting sick rooms, and as a local application to prevent septicemia during the parturient period, as well as at other times when there is reason to fear its development. By destroying the vitality of organized and living ferments, it prevents the occurrence of putrefaction, and arrests it when it has commenced. U.S. Environmental Protection Agency (EPA), "A Brief History of Thyme - Hungry History", "Sur la composition de l'huile essentielle de thym", "Ueber eine Synthese von Thymol aus Cuminol", "Biological Activities of Three Essential Oils of the Lamiaceae Family", "Thymol and carvacrol: biotransformation and antifungal activity against the plant pathogenic fungi Colletotrichum acutatum and Botryodiplodia theobromae", "Composition and Antimicrobial Activity of, "The Essential Oil of Monarda didyma L. (Lamiaceae) Exerts Phytotoxic Activity In Vitro against Various Weed Seeds", https://en.wikipedia.org/w/index.php?title=Thymol&oldid=986742896, GABAA receptor positive allosteric modulators, Articles with incomplete citations from August 2017, Short description is different from Wikidata, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles with unsourced statements from December 2019, Creative Commons Attribution-ShareAlike License, 49 to 51 °C (120 to 124 °F; 322 to 324 K), Iridoid glycosides (iridoids bound to a sugar), Terpene synthase enzymes (many), having in common a, This page was last edited on 2 November 2020, at 19:08. FORMULA: C10H14O. Ten drops of the solution will suffice for inhalation during 4 or 5 days. Blackie Academic Professional; London, UK: 1995. pp. It is not necessary to employ too strong a solution, as pure thymol possesses caustic properties. 58–59.

http://www.henriettes-herb.com - Copyright 1995–2020 Henriette Kress. [10] In the European Middle Ages, the herb was placed beneath pillows to aid sleep and ward off nightmares.

[19] This antibacterial activity is caused by inhibiting growth and lactate production, and by decreasing cellular glucose uptake. Ord.—Umbelliferae).

of thymol be heated in a test-tube, in a water-bath, with 5 Cc. Beilstein/REAXYS Number 1907135 . B. It is a crystalline white powder, but little soluble in water. M. Baelz, who has made some comparative experiments with thymol and salicylic acid (in the service of M. Wunderlich) upon persons in health, and also those affected with typhoid fever, articular rheumatism, phthisis, and pyelitis, states that in doses of ⅙ of a grain, repeated several times, no effect was observed; in order to obtain an appreciable therapeutical result, it was necessary to give daily from 25 to 30 grains.


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