Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levels. These foods and beverages include alcoholic beverages, especially beer, Chianti, and other red wines; alcohol-free beer; cheeses (especially strong, aged, or processed varieties); sauerkraut; yogurt; raisins; bananas; sour cream; pickled herring; liver (especially chicken liver); dried meats and sausage (including hard salami and pepperoni); canned figs; avocados; soy sauce; turkey; yeast extracts; papaya products (including certain meat tenderizers); fava beans; and broad bean pods. Larger servings of peanuts, brazil nuts and coconut may cause hypertension and headache according to the Micromedex database, but these foods have not been specifically studied in patients taking linezolid 1. Check with your doctor right away if blurred vision, difficulty in reading, or any other change in vision occurs during treatment with this medicine. If you become pregnant while taking linezolid, call your doctor. These foods and beverages include alcoholic beverages, especially beer, Chianti, and other red wines; alcohol-free beer; cheeses (especially strong, aged, or processed varieties); sauerkraut; yogurt; raisins; bananas; sour cream; pickled herring; liver (especially chicken liver); dried meats and sausage (including hard salami and pepperoni); Zyvox is expensive, especially for patients paying at a retail pharmacy. Last updated on Jul 2, 2021. Chris Martin Eats 1 Meal Per Day. Zyvox liquid (oral suspension) contains phenylalanine and could be harmful if you have phenylketonuria (PKU). To avoid this, do not eat large amounts of foods or drink beverages that have a high tyramine content (most common in foods that are aged, fermented, pickled, or smoked to increase their flavor, including aged cheeses, air-dried, fermented, or smoked fish, meat, or poultry, sauerkraut, soy sauce, red wine, or tap beer). Other studies have also found that fermented foods may be beneficial during antibiotic treatment. Call your doctor right away if you or your child feel very tired, weak, or nauseated, if you vomit or have trouble breathing, or if you feel lightheaded or fainting. https://www.mayoclinic.org/drugs-supplements/linezolid-oral-route/precautions/drg-20067254, Advertising and sponsorship opportunities, Hypertension (high blood pressure), uncontrolled or. Taking too many antibiotics can drastically change the amounts and types of bacteria within the gut microbiota, especially in early life (6, 7, 8). Zyvox injection is given as an infusion into a vein. Avoid brined and pickled vegetables and fruits including pickles, kimchee, sauerkraut and olives. 3 Commonly prescribed calcium channel blockers include Cardene (nicardipine), Cardizem (diltiazem), Norvasc (amlodipine), Procardia (nifedipine), and Verelan (verapamil . If this occurs, there are certain precautions your doctor may ask you to take, especially when your blood count is low, to reduce the risk of infection or bleeding: This medicine may cause infertility to men. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Zyvox only for the indication prescribed. Infection, Gram-negativeUse is not indicated in patients with this condition. The antibiotic linezolid, used to treat severe infections like pneumonia, may be inhibited by mature cheese and meat. If a list of these foods and beverages is not given to you, ask your doctor to provide one. Foods to Avoid When Taking Linezolid MENU Drugs & Medications Linezolid Food Interactions Linezolid Should I avoid certain foods while taking Linezolid? Linezolid 600 Tablet may be taken with or without food, but it is better to take it at a fixed time. For example, red wine contains antioxidant polyphenols, which are not digested by human cells but are digested by gut bacteria. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Copyright, 2023. This content does not have an Arabic version. amoxicillin, doxycycline, azithromycin, cephalexin, ciprofloxacin, metronidazole, clindamycin, Augmentin, ceftriaxone, amoxicillin / clavulanate. Do I need to change my diet whilst on linezolid? Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Sipping on a warm infusion of ginger tea may help relieve the stomach pain caused by antibiotics. Call your pharmacist for new medicine. Your eyes may need to be checked by an ophthalmologist (eye doctor). You should take it regularly as per the schedule prescribed by your doctor. It will be prescribed by a specialist doctor. Copyright: Merative US L.P. 1973, 2023. In turn, this can slow the rate at which medicines are absorbed (29). Copyright: Merative US L.P. 1973, 2023. This content does not have an English version. However, you should not flush this medication down the toilet. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. One study showed that probiotics can restore the microbiota to its original state after a disruptive event, such as taking antibiotics (17). This will be as an injection, or as a tablet or liquid medicine. Things to remember when you fill your prescription. Tyramine is present in certain foods. Call your doctor for medical advice about side effects. Benadryl works great for me but it does make me tired. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. 11. Minimally clinically significant. Promptly consult your doctor or pharmacist. If you are breastfeeding, tell your doctor if you notice diarrhea or vomiting in the nursing baby. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Do not stop taking linezolid without talking to your doctor. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. This medicine may cause a serious reaction called lactic acidosis (build-up of acid in the blood). They contain a number of healthy bacterial species, such as Lactobacilli, which can help restore the gut microbiota to a healthy state after antibiotics. This is because grapefruit juice and many medications are broken down by an enzyme called cytochrome P450. Avoid overripe bananas and any dish cooked with banana with the peels still on. This includes prescription and over-the-counter medicines, vitamins, and herbal products. ", Mayo Clinic: "Herbal supplements and heart medicines may not mix", Mayo Clinic: "What are the effects of drinking alcohol while taking antibiotics? They should be eaten after taking antibiotics but not during, as. However, other foods are not high in fiber but act as prebiotics by helping the growth of healthy bacteria like Bifidobacteria. May make these conditions worse. The dose is usually 10 milligrams (mg) per kilogram (kg) of body weight every 8 or 12 hours as determined by your doctor. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Do not shake the suspension. Fortunately, a number of studies have shown that taking probiotics, or live healthy bacteria, can reduce the risk of antibiotic-associated diarrhea (13, 14). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Similarly, cocoa contains antioxidant polyphenols that have beneficial prebiotic effects on the gut microbiota. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. To use the sharing features on this page, please enable JavaScript. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Additionally, you should avoid caffeinated foods like those containing chocolate. Linezolid is in a class of antibacterials called oxazolidinones. In our latest question and answer, the pharmacist gives information regarding the antibiotic Zyvox and potential food interactions. Check with your doctor right away if you have agitation, coma, confusion, decreased urine output, depression, dizziness, headache, hostility, increased thirst, irritability, lethargy, muscle pain or cramps, muscle twitching, nausea or vomiting, rapid weight gain, seizures, stupor, swelling of the face, ankles, or hands, or unusual tiredness or weakness. Vancomycin-resistant enterococcal (VRE) infections, MRSE (Methicillin-resistant Staphylococcus aureus). Linezolid comes as a tablet and oral suspension (liquid) to take by mouth. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. There have been certain adverse reactions linked to the drugs use for infections caused by gram negative organisms and it should be avoided in those situations. There are 12 disease interactions with linezolid which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Zyvox, while easily dosed, does have restrictions when it comes to food intake. Do not shake. Ask your doctor what you should do if this happens. You may report side effects to FDA at 1-800-FDA-1088. Check with your doctor immediately if you think you or your child are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Our website services, content, and products are for informational purposes only. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. When protein begins to break down, tyramine is formed, according to the Micromedex database. One study found that consuming red wine polyphenol extracts for four weeks could significantly increase the amount of healthy Bifidobacteria in the intestines and reduce blood pressure and blood cholesterol (31). Unlike probiotics, which are live microbes, prebiotics are foods that feed the good bacteria in your gut. Can I Take Vitamins If I Am Taking Antibiotics? 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). I've heard of non-drowsy Benadryl but can't find it anywhere. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. You may feel weak, drowsy, confused, anxious, or very hungry. This means that the medication could potentially stay in your body for too short, or too long, a time, rendering it either useless, or else potentially lethal. Available for Android and iOS devices. Advertising revenue supports our not-for-profit mission. Drug information provided by: Merative, Micromedex. It is used to treat infections of the lungs (pneumonia), skin, and soft tissues. Good bacteria in your gut example, red wine contains antioxidant polyphenols, which are not high in fiber act... Of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland linezolid 600 may! Some of these side effects this condition Web Advertising help support our mission been in... 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