Verify the tympanic membrane is intact prior to administration. CLARO™ Otic Solution is a fixed combination of three active substances: florfenicol (antibacterial), terbinafine (antifungal), and mometasone furoate (steroidal anti-inflammatory). Reevaluate the dog if hearing loss or signs of vestibular dysfunction are observed during treatment. Twist the cap to break the seal and then remove cap from the dropperette. Gently massage the base of the ear to allow distribution of the solution. Turn the cap over and push the other end of the cap onto the tip of the dropperette. CLARO ® Otic Solution is a fixed combination of three active substances: florfenicol (antibacterial), terbinafine (antifungal), and mometasone furoate (steroidal anti-inflammatory). CLARO ® solution is supplied in a single-use dropperette in a blister. The use of CLARO® in dogs with perforated tympanic membranes has not been evaluated. The compatibility and additive effect of each of the components in CLARO® solution was demonstrated in a component effectiveness and non-interference study in vitro study of organisms collected from clinical cases of otitis externa in dogs enrolled in the clinical effectiveness study determined that florfenicol and terbinafine hydrochloride inhibit the growth of bacteria and yeast commonly associated with otitis externa in dogs. Shake before use.CLARO® should be administered by veterinary personnel.Administer one dose (1 dropperette) per affected ear. Use with caution in dogs with impaired hepatic function (see ANIMAL SAFETY on label). Turn the cap over and push the other end of the cap onto the tip of the dropperette. The integrity of the tympanic membrane should be confirmed before administering the product. Do not administer orally. The product labeling information includes all published material associated to a drug. Each dropperette contains one 1 mL dose. Do not use in dogs with known or suspected hypersensitivity to florfenicol, terbinafine hydrochloride, mometasone furoate, other corticosteroids or any excipients. Bayer, the Bayer Cross and CLARO are registered trademarks of Bayer. The addition of mometasone furoate to the combination did not impair antimicrobial activity to any clinically significant extent. Behavior and Stress Training and Solutions. 2.
Florfenicol is a bacteriostatic antibiotic which acts by inhibiting protein synthesis. CLARO® Otic Solution is a fixed combination of three active substances: florfenicol (antibiotic), terbinafine (antifungal) and mometasone furoate (steroidal anti-inflammatory).
Claro Otic Solution Animal Product Label Images Screw the applicator nozzle onto the dropperette - image 01 Insert the tapered tip of the dropperette into the affected external ear canal and squeeze to instill the entire contents (1 mL) into the affected ear. CLARO® Otic Solution is a fixed combination of three active substances: florfenicol (antibacterial), terbinafine (antifungal), and mometasone furoate (steroidal anti-inflammatory). Prior to treatment, the ear(s) was cleaned with saline.
Florfenicol, Terbinafine hydrochloride, and Mometasone furoate Otic Solution. The duration of effect should last 30 days.1.Clean and dry the external ear canal before administering the product.2.Verify the tympanic membrane is intact prior to administration.3.Remove single dose dropperette from the package.4.While holding the dropperette in an upright position, remove the cap from the dropperette.5.Turn the cap over and push the other end of the cap onto the tip of the dropperette.6.Twist the cap to break the seal and then remove cap from the dropperette.7.Screw the applicator nozzle onto the dropperette.8.Insert the tapered tip of the dropperette into the affected external ear canal and squeeze to instill the entire contents (1 mL) into the affected ear.9.Gently massage the base of the ear to allow distribution of the solution.10.Repeat with other ear as prescribed.Cleaning the ear after dosing may affect product effectiveness. CLARO® should be used with caution in dogs with impaired hepatic function (see ANIMAL SAFETY). Screw the applicator nozzle onto the dropperette - image 01, Insert the tapered tip of the dropperette into the affected external ear canal and squeeze to instill the entire contents (1 mL) into the affected ear. Although all adverse reactions are not reported, the following information is based on voluntary post-approval drug experience reporting. 6. Human Warnings: Not for use in humans. Terbinafine is an antifungal which selectively inhibits the early synthesis of ergosterol. By system, adverse events are listed in decreasing order of frequency. While holding the dropperette in an upright position, remove the cap from the dropperette. 7. This product requires a veterinarian's prescription. All Behavior and Stress Training and Solutions, All Behavior & Stress Training /Solutions, Single-dose regimen does not require additional treatment visits, A single, 1mL dose in each affected ear treats all dog sizes, A clear, liquid solution — no gunk or opacity to impair visualization on recheck, Manage your pets, vets, and prescriptions for easy checkout. 3. 5. The integrity of the tympanic membrane should be confirmed before administering the product.
Avoid contact with eyes. Claro™ (florfenicol, terbinafine, mometasone furoate) Otic Solution features the only FDA-approved, veterinarian-administered, single-dose treatment regimen for canine otitis externa.
Caution should be used to prevent the medication from getting into the eyes of the dog being treated. Florfenicol is a bacteriostatic antibiotic which acts by inhibiting protein synthesis. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 30 Sep 2020) and others. Clean and dry the external ear canal before administering the product. Human Warnings: Not for use in humans. The dogs were evaluated on Days 0, 7, 14, and 30. Humans with known hypersensitivity to florfenicol, terbinafine hydrochloride, or mometasone furoate should not handle this product.
7. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Each dropperette contains one 1 mL dose. JavaScript seems to be disabled in your browser.
The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 8.
May cause eye irritation. Antibacterial, antifungal, and anti-inflammatoryFor Otic Use in Dogs Only. CLARO® contains 16.6 mg/mL florfenicol, 14.8 mg/mL terbinafine (equivalent to 16.6 mg/mL terbinafine hydrochloride) and 2.2 mg/mL mometasone furoate. We comply with the HONcode standard for trustworthy health information -, 905-282-5550 or 800-62BAYER (800-622-2937), Direction and dosage information for Claro. Twist the cap to break the seal and then remove cap from the dropperette. should be administered by veterinary personnel. Insert the tapered tip of the dropperette into the affected external ear canal and squeeze to instill the entire contents (1 mL) into the affected ear. Of the 183 dogs included in the effectiveness evaluation, 72.5% of dogs administered CLARO® solution were successfully treated, compared to 11.1% of the dogs in the vehicle-control group (p=0.0001). In case of accidental skin contact, wash area thoroughly with water. Reevaluate the dog if hearing loss or signs of vestibular dysfunction are observed during treatment.Use of topical otic corticosteroids has been associated with adrenocortical suppression and iatrogenic hyperadrenocorticism in dogs (see ANIMAL SAFETY).Use with caution in dogs with impaired hepatic function (see ANIMAL SAFETY).The safe use of CLARO® in dogs used for breeding purposes, during pregnancy, or in lactating bitches has not been evaluated. Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. The integrity of the tympanic membrane should be confirmed before administering the product.
In case of accidental ingestion by humans, contact a physician immediately. CLARO® is supplied in a single-use dropperette in a blister. 8. CLARO ® Otic Solution is a fixed combination of three active substances: florfenicol (antibacterial), terbinafine (antifungal), and mometasone furoate (steroidal anti-inflammatory). In case of accidental skin contact, wash area thoroughly with water. Florfenicol is a bacteriostatic antibiotic which acts by inhibiting protein synthesis. Monday-Friday 8am-5pm CST + Saturday 8am-1pm. The duration of effect should last 30 days. Not for use in humans.
In a well-controlled, double-masked field study, CLARO® was evaluated against a vehicle control in 221 dogs with otitis externa. Description Claro® (florfenicol, terbinafine, mometasone furoate) Otic Solution features the only FDA-approved, veterinarian-administered, single-dose treatment regimen for canine otitis externa associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (Staphylococcus pseudintermedius). 6. CLARO® contains 16.6 mg/mL florfenicol, 14.8 mg/mL terbinafine (equivalent to 16.6 mg/mL terbinafine hydrochloride) and 2.2 mg/mL mometasone furoate.Inactive ingredients include purified water, propylene carbonate, propylene glycol, ethyl alcohol, and polyethylene glycol. Administer one dose (1 dropperette) per affected ear. Insert the tapered tip of the dropperette into the affected external ear canal and squeeze to instill the entire contents (1 mL) into the affected ear. No consistent synergistic or antagonistic effect of the two antimicrobials was demonstrated. Product was successfully added to your shopping cart. Store between 20°C-25°C (68°F-77°F), excursions permitted 10°C-30°C (59°F-86°F). CLARO® is indicated for the treatment of otitis externa in dogs associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (Staphylococcus pseudintermedius). CLARO ® is available in cartons of two, ten, or twenty dropperettes. The safe use of CLARO® in dogs used for breeding purposes, during pregnancy or lactation has not been evaluated. No clinically relevant treatment-related findings were noted in hearing tests, body weight, weight gain, or food consumption. In case of accidental contact with eyes, rinse with abundant quantities of water and seek medical attention. One hundred and forty six dogs were treated with CLARO® and 75 dogs were treated with the vehicle control. Cleaning the ear after dosing may affect product effectiveness. CLARO® is available in cartons of 2 or 10 dropperettes. In case of accidental ingestion, contact a physician immediately. 4. Remove single dose dropperette from the package. Treatment (1 mL) was administered once on Day 0 to the affected ear(s). The use of CLARO® in dogs with perforated tympanic membranes has not been evaluated. Every effort has been made to ensure the accuracy of the Claro information published above. CLARO® should be administered by veterinary personnel. Keep out of reach of children.